The FDA is said to have recently instituted a crack down on weight loss supplements as a result of serious uncomfortable side effects and even death linked to some dietary supplements like ephedra. The ban on ephedra merchandise resulted to the introduction of so-called ephedra free weight loss supplements, these too are said to yield their own fair share of troubles and they too could be destined to a similar fate as ephedra.

These ephedra free supplements have been shown to bring about an increase in heartbeat and a couple other negative effects on healthy people according to a health specialist who was in the research.

The investigation conducted with the University of California at Berkeley was the first one to check out the health effects of reformulated weight loss supplements. Among the things tested for included hypertension and pulse rate of volunteers who were given reformulated weight loss supplements produced from extracts of bitter orange.

Since the ban slapped on ephedra by FDA, an ever-increasing number of body fat loss product manufactures have turned to extracts of bitter orange. The USB study required 20 healthy volunteers, who received individual doses of a weight loss supplement or a placebo.

The diet supplements used in the study were Xenadrine EFX and Advantra Z, each of which incorporates bitter orange extracts. The administered drug was shown to influence an increase in cardio pulse rate all the way to 16 beats in one minute. The Thermogenic Xenadrine EFX for example was shown to rev up heart rate by 13 per cent, an element that makes it almost similar in performance to ephedra.

Bitter orange extracts include synephrine, a component contained in over 90% of citrus fruits but found in higher concentrations in fruits such as Sour orange, Zhi shi and bitter orange and which is widely used as a remedy in the treatment of respiratory tract congestion and hypertension. Xenadrine EFX includes a stimulant in the part, usually caffeine. The quantity of caffeine is Xenadrine is believed to be the equivalent of 3 coffee cups. This is the ingredient to blame for the surge in blood pressure and individuals using this product are informed against over dosage.

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